Pilot Fermentor
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- Pilot Fermentor
Pilot Fermentor
High Flexible Small bench top system suitable for research And Industry for both Microbial and cell culture application
- Ideal system for trouble free operation
- Well equipped for batch , fed batch & continuous
- Minimal Foot print
- Up gradation for multiple system
- Flexible control system for customized function
- Open end OPC server – integrate with other device
- Biojenik SCADA user friendly mimics
- Complete Data Management
- Compliance 21 CFR part 11
- Suitable for both microbial/cell culture
- Multiple feeding/gas lines
- All ports and plugs stand for international std
- Sampling either from bottom or top or both
Servo motors ensure minimum and max. speed Without affecting the torque
Vessel
- Vessel Insitu- sterilizable single glass vessel , SS vessel ( on request)
Top and bottom with SS LID with necessary ports and plugs - Volume Total volume: 2.4 and 3.5 (3.1 on request)
- Drive assemble 4x baffles attached with top lid or around the vessel wall SS 316L
- Bottom Driven Direct drive Single Mechanical Seal Servo/DC motor
Speed: 25 to 3000 rpm - Top Driven Direct drive Single Mechanical seal Servo/DC motor
Speed 25 to 3000 rpm - Air Bubble mixing shear free mixing achieved by air bubbles instead of mechanical
Agitator - Impeller Marine Type for Axial flow mixing ( on request)
Pitch Blade for Axial flow mixing ( on request)
Rushton type for radial flow mixing . 6 blade x 2nos - Heating/cooling Electrical heating finger x 800 Watts 1 no. Or 400 Watts x 2nos
Control for both Sterilization and culture temperature
Cooling finger suit for water circulation with on/off Electrical
Pulsed valve. Safety hood in SS - Aeration Straight Tube: Submerged aeration for efficient dispersion bubbles
Ring Sparger: submerged aeration for superior dispersion bubbles
Sintered Sparger: submerged fine efficient low gas flow
Filter: Cartridge Ceramic tube and Sintered SS with SS housing (0.2μ) - Gas Supply Module Single gas line
2 Gas Mixing station
4 Gas mixing station
4 Gas mixing and 2 Gas overlay - Gas control Four Gas combined with 1x MFC
Individual gas with MFC
Individual gas with pulsed valv - Gas line accessories Gas pressure control valve, Check valve, Pressure gauge, Flowmeters
Hypodermic needle, sterile needle (Replace the hypodermic needle) - Gas ranges Air: 2 vvm O2: 0.5 vvm N2: 1vvm CO2: 0.1vvm
Various ranges can be selected (as per process requirement) - Gas Exhaust Absolute filter (99.9999%) cartridge with SS housing with back pressure
Control valve (Manual or Auto)
Gas Condenser: water cooled condenser - Feed system 4 x Fixed speed pump, 1 x Variable speed pump
Additional Pump up to 6 Fixed speed, 1 x Variable speed ( on request)
Sterile Cap with bottle: 250ml, 500ml 1000ml bottle with SS cap or PP cap
With vent filter
Height adjustable Dip tube immersed at the liquid bottom for
Harvest /sampling - Rotor filter Cell retention filter ( pore size 20μm onwards) fixed with shaft itself.
- Sampling/harvest Dip tube with pinch cock assembly. (by Positive vessel pressure)
Hypodermic needle septum collection from bottom
Push back valve at the bottom
Control Module
- Speed controller Direct Digital control system, Measurement and control cascaded with DO
Controller. HMI via JENIK SCADA
18. - Temperature controller Suitable for both SIP and process temperature by activate the
Cooling/ heating valve. Operate by JENIK SCADA
Measurement : 0 to 150 Degree C 19. - PH controller Sterilizable Gel type PH probe, activate the Acid, base dosing pump
Operation via JENIK SCADA Measuring range: 2 to 12PH
20. - DO controller Poloragraphic or Optical sensor enable to activate the final element
Pulsed valve or MFC . Cascade with Gas mixing station, Agitator and
Back pressure control valve. Measurment: 0 to 100%
Control via JENIK SCADA - Antifoam/level Conduct type height adjustable probe activate antifoam correction
Agent pump. For level activate the feed addition or harvest pump
Control via JENIK SCADA
22. - Redox/RH Sterilizable ORP probe controller activate the dosing pump or valve
Measurment range: + 400 to -400mV Control via JENIK SCADA
23. - Optical Density Sterilizable Turbidity measurement probe activate dosing pump or valve
Measurement: 0 to 250g/L . Control via - JENIK SCADA
24. JENIK SCADA Software with process controller functions
Customized operator interface, Display all process and set point
values. Profile, cascade and manual operation
Alarm and event for all parameters and deviation
Different Access level, Recording and analyzing,
Online recording all the set Point and measurement value,
trend and text data Data can be exported to excel sheet
Recording and analyzing, Online recording all the set point
and measurement value, trend and text data Data can be exported to
excel sheet
One System is capable to operate up to 8 Fermenter
25. - Hardware Suitable PC or Laptop with inbuilt OS –windows with run time
License with std. system configuration suitable to operate the
Software ( JENIK SCADA)
Accessories
- Exit Gas Analyzer O2 measurement ( 0 to 25%) Co2 Measurement (0 to10%)
Suitable to connect upto 4 fermenter. Suitable I/O connect
with JENIK SCADA for data logging - Load cell Platform type weighing measurement of the liquid bottle or
Fermenter. Accuracy ± 0.01g. Operate via JENIK SCADA
Cascade operation with dosing pump - Ports and Needle 12mm std ports, 12mm Needle.( 3mm and 4.5mm)
- Impellers Rushton, Marine, Pitch blade ( 40mm,48mm and 60mm )
Six blade, Four blade and two blade. - Light Hood SS hood with LED , adjustable Intensity 0 to 100% from SCADA
- Chiller Suitable to operate one fermenter ( 800W) with 20 Lts tank
Heat Load Delta T 10 Degree C
Available the capacity to operate up to 8 Fermenter - Compressor 10LPM @ 2bar with storage tank 25Lts including pressure regulator Pressure gauge, Moisture trap. Available higher capacity : to operate up to 8 fermenter
Lb-Icc-150L
Specification:
- Capacity – 150 L
- Temperature Range – 5-50°C (Light off), 10-50°C (Light on)
- Temperature Accuracy – ±0.5°C
- Temperature Uniformity – ±2°C
Lb-Icc-250L
Specification:
- Capacity – 250 L
- Temperature Range – 5-50°C (Light off), 10-50°C (Light on)
- Temperature Accuracy – ±0.5°C
- Temperature Uniformity – ±2°C
Lb-Icc-350L
Specification:
- Capacity – 350 L
- Temperature Range – 5-50°C (Light off), 10-50°C (Light on)
- Temperature Accuracy – ±0.5°C
- Temperature Uniformity – ±2°C